Xanthium sibiricum Fructus Xanthii, Cang Er Zi

Cockleburs (Xanthium) are a genus of flowering plants that grow in the Americas and eastern Asia. Xanthium is an herb used for the treatment of acute and chronic rhinitis and chronic paranasal sinusitis. Xanthium herb is commonly added to formulations that soothe skin conditions with itching, including atopic dermatitis and chronic eczema.

What the herb contains
Xanthium sibiricum fruit has xanthatin, xanthiazinone, xanthiazone, xanthiside, xanthienopyran and 5-hydroxypyrrolidin-2-one along with eremophilanolides, sibiriolides A and B.

Human studies with Xanthium sibiricum herb could not be found as of 2009.

Two new eremophilanolides from Xanthium sibiricum.
Nat Prod Res. 2006 Nov; Zhang XQ, Ye WC, Jiang RW, Yin ZQ, Zhao SX, Mak TC, Yao XS. Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, PR China.
Two new eremophilanolides, sibiriolides A (1) and B (2), were isolated from the aerial parts of Xanthium sibiricum.

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