Weight Loss Study - A review of research with diet, carbohydrates, fats, protein, green tea and other natural supplements

There have been countless weight loss studies and many more are ongoing. This page discusses interesting and practical weight loss studies. If you are unable to reduce your caloric intake by yourself, consider Diet Rx, a highly effective appetite suppressant.

Reducing calories and exercise
Cutting calories and exercise for weight loss are the best options for the long haul. In an analysis of dozens of weight loss studies, statisticians found that approaches that focused on trimming calories -- with or without exercise -- were most effective at keeping the pounds off over several years. On average, participants in these weight loss studies shed 11 to 19 pounds at most, then typically gained a little bit back over time. Diet and exercise changes can work over the long haul, if people keep them up and have realistic expectations. Journal of the American Dietetic Association, October 2007.

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Weight loss study - Losing abdominal fat
Those who have a healthy diet and regularly engage in physical activity have less abdominal fat, including those deep layers of belly fat that are especially unhealthy. Among nearly 3,000 middle-aged adults, those who maintained a healthy diet -- including lots of fruits, vegetables, whole grains and low-fat dairy -- had less abdominal fat than those with poor diets. Like healthy eaters, exercisers have less abdominal fat just below the skin, as well as less visceral fat -- deep layers of fat that surround the abdominal organs and are especially likely to contribute to diseases like diabetes and heart disease. Esther A. Molenaar of the University Medical Center Utrecht, in the Netherlands, led the study published in Diabetes Care, March 2009.

Weight loss study, low fat or low carbohydrate?
The effects of a low-fat versus a low carbohydrate diet in obese adults.
Med Clin (Barc). 2009 February. Red temática de Investigación Corporativa en Envejecimiento RD056/0013, Instituto de Endocrinología y Nutrición, Facultad de Medicina, Universidad de Valladolid, Unidad de Investigación, Hospital Río Hortera, Valladolid, España.
The aim of our study was to compare the effect of a high fat and a high protein diet vs a fat restricted diet on weight loss in obese patients. A population of 74 obesity non diabetic outpatients was analyzed in a prospective way. Patients were randomly allocated to two groups: a) diet I (low fat diet: 1500kcal/day, 52% carbohydrates, 20% proteins, 27% fats) with a distribution of fats and b) diet II (high fat and high protein diet: 1507kcal/day, 38% carbohydrates, 26% proteins, 36% fats). After three months with diet, weight, blood pressure, glucose, C reactive protein, insulin, insulin resistance, total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides were evaluated. There were randomized 35 patients (4 males and 31 females) in the group I and 39 patients (6 males and 33 females) in diet group II. In group I, systolic pressure, BMI, weight, fat free mass, fat mass total body water, intracellular body water and waist circumference decreased significantly. In group II, glucose, total cholesterol, LDL cholesterol, systolic blood, BMI, weight, fat mass, total body water and waist circumference decreased significantly. Differences among averages of parameters before treatment with both diets were not detected. No differences were detected on weight loss between a fat-restricted diet and a high fat and high protein enhanced diet.

Eating an apple before a meal
An apple a day helps you eat fewer calories. People who eat an apple before a meal consume 150 to 200 fewer calories than when they don't have the apple. This may also apply to other high fiber fruits or vegetables. Researchers at Pennsylvania State University did a weight loss study to determine if eating an apple in different forms affects calorie intake. Before breakfast and lunch, normal-weight men and women were given either nothing, 1½ medium peeled, cut-up apples (about 125 calories), or a similar caloric amount of applesauce, apple juice with added fiber or apple juice without fiber. About 15 minutes later, participants were served an entree of cheese tortellini and tomato sauce. Participants who had the raw apple consumed fewer calories than at the meals when they had applesauce, juice or nothing.

Weight loss study with emotional eaters
Emotional eaters -- people who eat when they are lonely or blue -- tend to lose the least amount of weight and have the hardest time keeping it off. This weight loss study may explain why so many people who lose weight gain it all back.

Weight loss study and teenagers
Overweight teenagers are more likely to continue practicing extreme eating or weight-control measures when their parents focus too much weight issues. However, family sit-down meals and regular eating patterns protect teenagers from continued weight-related problems. Parents should talk less about weight loss and do more to make the home environment one in which it is easy to engage in healthy eating habits.

Weight loss study in older people
Obese older adults who lose weight also tend to lose bone mass, even if they exercise regularly.

Weight loss study - bariatric surgery can lead to increased longevity
Substantial Intentional Weight Loss and Mortality in the Severely Obese.
Ann Surg. 2007 Dec.
Significant weight loss following bariatric surgery improves the illnesses associated with obesity. Improved survival as a result of surgical weight loss has yet to be clearly demonstrated using clinical data. The surgical weight loss cohort was a series of consecutive patients treated with a laparoscopic adjustable gastric band in Melbourne between June 1994 and April 2005. The Melbourne Collaborative Cohort Study (MCCS) provided a community control cohort, recruited between 1992 and 1994 and followed to June 2005 to determine vital status. The review of studies shows substantial surgical weight loss in a morbidly obese population was associated with a significant survival advantage.

Surgery results from different hospitals
People who have weight loss surgery at a hospital designated as a center of excellence lose the same amount of weight as their peers treated at non-designated hospitals, but pay more. Medicare and Medicaid patients undergoing weight loss or "bariatric" procedures are required to have their surgery at a center of excellence. To be named a bariatric surgery center of excellence the hospital must keep a database of patient outcomes, staff extra personnel to run the program, and perform at least 125 operations annually. Dr. Edward H. Livingston, from the University of Texas Southwestern School of Medicine in Dallas, used data from the US National Inpatient Survey to compare outcomes of bariatric surgery at hospitals centers of excellence and hospitals that were not. In 2005, 24 of 253 named hospitals were designated as a bariatric surgery center of excellence; 28 percent of 19,363 bariatric operations were performed at centers of excellence. The average cost per patient was significantly higher in the designated centers. Death rates and complication rates were no different between the centers of excellence hospitals and the hospitals that were not centers of excellence. Archives of Surgery, April 2009.

Weight loss study and sleep apnea
In people who are obese, weight-loss surgery will likely lead to an improvement in obstructive sleep apnea (OSA) but it won't eliminate the nighttime breathing disorder. Many patients will have residual obstructive sleep apnea one year after weight-loss surgery. Journal of Clinical Sleep Medicine, August 15, 2008.

Smoking
Cigarette smoking enhances the activity of a gene that helps break down body fat. Compared with non-smokers, a group of healthy smokers showed greater activity in a gene called AZGP1 in cell samples taken from their airways. Because the gene is thought to be important in breaking down fat and controlling weight, the findings point to one possible reason that smokers tend to weigh less than non-smokers -- and why people often put on pounds after quitting.  Chest, May 2009.

Weight loss reduces risk for colon cancer
Obesity is associated with an increased risk of colorectal adenomas -- growths or polyps that can become cancerous -- but weight loss might reduce the risk for these growths and hence weight loss may reduce the risk for colon cancer.. American Journal of Gastroenterology, August 2008.

Weight loss study - the low fat diet guidelines may contribute to obesity
National guidelines advising Americans to eat a low-fat diet as a way for weight loss or health maintenance have had the unintended consequence of feeding the current obesity epidemic. The federal government has issued official dietary guidelines every five years since the late 1970s. In 1990, a recommendation was added that people should get less than 30 percent of their daily calories from fat. The guidelines -- particularly those on fat -- may have done more harm than good. American Journal of Preventive Medicine, online January 22, 2008.


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