Rhamnus purshiana bark, herbal laxative Cascara Sagrada bark
Rhamnus purshiana bark is an herbal laxative that contains anthraquinones. Anthraquinone glycosides are poorly absorbed from the gastrointestinal tract but are cleaved by gut bacteria to produce aglycones (such as emodin) that are more readily absorbed and are responsible for the purgative properties of these preparations. See Cascara-Sagrada bark supplement to purchase this product. Also consider psyllium fiber as an excellent motility agent to help reduce problems with constipation.
Rhamnus purshiana bark components
Glycograngulin, anthraquinone glycosides of emodin, emodinanthrone and aloe-emodin,
anthracene derivatives. Emodin is a naturally occurring anthraquinone present in
the roots and bark of numerous plants of the genus Rhamnus. Extracts from the
roots, bark, and/or dried leaves of buckthorn, senna, cascara, aloe, frangula,
and rhubarb have been used as laxatives since ancient times and currently are
widely used in the preparation of herbal laxative preparations.
Rhamnus purshiana drug interaction
Anthranoid-containing plants including Cassia senna and Rhamnus purshiana and
soluble fibers including guar gum and psyllium can decrease the absorption of
drugs.
Rhamnus species
R alpina L.
Rhamnus fallax boiss
R frangula L. has glycosides of chrysophanoldianthrone and
chrysophanolphys-ciondianthrone and glycosides of emodin and emodinanthrone.
Rhamnus purshiana DC.
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