Acomplia side effects, dosage, review, research studies, insomnia, depression, dry mouth and headaches
Patients taking the Sanofi-Aventis anti-obesity drug
Acomplia, known generically as rimonabant, are likely to suffer Acomplia side
effects such as
depression and anxiety. Another Acomplia side effect is an increased
amount of suicidal thoughts. Acomplia -- also known by the brand name Zimulti in the United States -- is the
first in a new class of weight
loss pill drugs that switch off the same brain circuits that make
people hungry when they smoke cannabis.
A study in the British Medical Journal found that people taking Acomplia
anti obesity
drug
would only see "modest" weight loss
with many remaining significantly obese or overweight.
Opinion on the benefit and risk
of Acomplia
Is rimonabant Acomplia efficacious and safe in the treatment of obesity?
Expert Opin Pharmacother. 2008 October. Doggrell SA. RMIT University, School
of Medical Sciences, Discipline of Pharmaceutical Sciences, Bundoora, Victoria
3083, Australia.
This evaluation is of the Acopmlia
Rimonabant
in Obesity (RIO) programme of clinical trials, and of the first trial to
determine whether rimonabant Acomplia has any effect on a clinical outcome. At
present, it is doubtful whether the benefits of rimonabant outweigh the risks
and side effects. Unless rimonabant is shown to have benefits in ongoing
clinical outcome studies, there is little rationale to support its use in the
treatment of obesity.
Acomplia side effects, caution, risks, danger
In November of 2007,
Danish researchers reviewed four published studies featuring 4,100 patients and found that
people taking Acomplia 20 milligrams per day were twice more likely to
discontinue treatment due to depressive disorders and three times more likely to
stop because of anxiety than those who received a placebo.
In addition to depression and anxiety, Acomplia side effects include dry mouth
and headaches.
Sleep problems with Acomplia
Sleep disorders associated with treatment with rimonabant
Rev Neurol. 2008 Oct 16-31;47(8):446. Sempere AP, Giner-Bernabeu JC,
Berenguer-Ruiz L, Selles-Galiana MF, Hernandez-Rubio L, Lezcano-Rodas M. Sempere
AP, Giner-Bernabeu JC, Berenguer-Ruiz L, Selles-Galiana MF, Hernandez-Rubio L,
Lezcano-Rodas M.
Acomplia anti
obesity pill - Sanofi-Aventis has seen strong demand for new obesity pill
Acomplia since its launch in Britain in late June, 2006. Acomplia, which
switches off brain circuits that make people hungry when they smoke cannabis, is
viewed as Sanofi's most important new product, with potential annual sales
global of more than $3 billion. As a treatment for obesity, the latest diet-aid
drug, Acomplia, produces only moderate weight loss, according to a review of
clinical trial results in October 2006. Acomplia, made by Sanofi-Aventis, is
known generically as rimonabant. It was approved for use in the European Union
earlier in 2006.
Novermber 2006 - Sanofi-Aventis's new obesity pill Acomplia is
selling well in Britain and Ireland. In Germany, however, insurers have
dismissed Acomplia as a "lifestyle" treatment and are refusing reimbursement.
Acomplia switches off the same brain circuits that make people hungry when they
smoke cannabis.
November 2006 - Acomplia (rimonabant) is approved in Mexico to
treat obese/overweight patients with associated type 2 diabetes or dyslipidemia
or to help them improve glycemic control on background of conventional
antidiabetic treatment
April 2008 - The Sanofi-Aventis weight loss drug rimonabant does
not slow heart disease in obese patients with fat around the middle, and
Acomplia side effects include anxiety and depression. More than 40 percent of
patients who take Acomplia, develop psychiatric side effects.
A supplement with herbs as an excellent alternative to anti obesity medications is a doctor formulated product called Diet Rx.